Factors Associated with TB-HIV/AIDS Co-Infection in Kedu, Central Java


Tuti Susilowati1), Tri Nur Kristina2), Muchlis AU Sofro3)

 

1)Doctoral Program in Medical and Health Sciences, Universitas Diponegoro

2)Faculty of Medicine, Universitas Diponegoro

3)Dr Karyadi General Hospital Semarang, Central Java

 

ABSTRACT

Background: TB-HIV co-infection is one of the current biggest public health chal­­lenges in the world.  Although there is a breadth of information on TB-HIV co-infection among settled populations elsewhere, to our knowledge, there are no pub­­lished reports on the determinants of TB-HIV co-infection from Central Java, In­­do­nesia. This study aimed to determine the factors associated with TB-HIV/AIDS co-infection in Kedu, Central Java.

Subjects and Method: This study was a case control study conducted at ge­ne­ral hospital in Kedu, Central Java. A sample of 152 patients with HIV was se­lec­ted for this study consisting those with and without TB-HIV co-infection. The de­pen­dent variable was TB-HIV/ AIDS co-infection. The independent variable were edu­cation level, history of TB contact, BCG immunization status, opportunistic in­­fec­tion, adherence to treatment, drug taking supervisor support, and com­mu­nity health worker support. The data were collected from medical record and ques­tionnaire. The data were analyzed by a multiple logistic regression.

Results: TB-HIV/AIDS co-infection was associated with low education (OR= 4.70; CI= 95%; 2.11 to 10.47 p= 0,001), history of TB contact (OR= 3.75; CI= 95%; 1.26 to 5.72; p= 0.01), abscence of BCG immunization (OR= 3.59; CI= 95%; 1.07 to 6.23; p= 0.033), opportunistic infection (OR= 3.42; CI= 95%; 1.23 to 5.89; p= 0.010), non-adherence to treatment (OR= 5.15; CI= 95%; 1.50 to 7.16; p= 0.001), lack of drug taking supervisor support (OR= 4.61; CI= 95%; 1.94 to 10.50; p= 0.001), and lack of community health worker support (OR= 4.51; CI= 95%; 1.94 to 10.50; p= 0.001).

Conclusion TB-HIV/AIDS co-infection is associated with low education, history of TB contact, abscence of BCG immunization, opportunistic infection, non-adherence to treatment, lack of drug taking supervisor support, and lack of com­mu­­nity health worker support.

Keywords: risk factors, Tuberculosis-HIV/AIDS co-infection

Correspondence: Tuti Susilowati. Doctoral Program in Medical and Health Sciences, Universitas Diponegoro, Semarang, Central Java. Email: Iyya_salaman@yahoo.co.id. Mobile: 081357337149

DOI: https://doi.org/10.26911/theicph.2018.01.25

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