Risk Factors of Tuberculosis: A New Path Analysis Evidence from Ponorogo, East Java

Diana Sayidah1), Setyo Sri Rahardjo2), Bhisma Murti1)


1)Masters Program in Public Health, Universitas Sebelas Maret

2)Faculty of Medicine, Universitas Sebelas Maret



Background: Tuberculosis remains a major health problem worldwide. In 2016, 6.3 million new cases of TB were reported (up from 6.1 million in 2015), equi­va­lent to 61% of the estimated incidence of 10.4 million. This study aimed to deter­mi­ne risk factors of tuberculosis in Ponorogo, East Java, using a path analysis mo­­del.

Subjects and Method: This was a case control study conducted in Ponorogo, East Java, from April to May 2018. A sample of 200 study subjects was selected for this study by fixed disease sampling, consisting of 100 adults with tuberculosis and 100 adults without tuberculosis. The dependent variable was tuberculosis. The independent variables were age, gender, education, nutritional status, dwel­ling density, smoking, and alcohol drinking. Data on tuberculosis infection status were obtained from the medical record at District Health Office Ponorogo. The da­ta were collected by questionnaire and analyzed by path analysis model on Sta­ta 13.

Results: The risk of tuberculosis increased with BMI ≥25 (b= 2.50; 95% CI= 0.51 to 4.50; p= 0.014), smoking (b= 2.42; 95% CI= 0.74 to 4.11; p= 0.005), lack of ligh­ting (b= 3.11; 95% CI= 1.34 to 4.86; p= 0.001), alcohol drinking (b= 2.15; 95% CI= 0.75 to 3.56; p= 0.003), densed dwelling (b= 2.31; 95% CI= 0.69 to 3.92; p= 0.005), and age ≥44 years (b= 1.51; 95% CI= -0.01 to 3.02; p= 0.051). The risk of tu­ber­­culosis was indirectly affected by education.

Conclusion: The risk of tuberculosis increases with BMI, smoking, lack of lighting, alcohol drinking, dwelling density, and age ≥44 years.

Keywords: tuberculosis, age, dwelling density, smoking, alcohol drinking, education

Correspondence: Diana Sayidah. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami No. 36 A, Surakarta 57126, Central Java. Email: dianasayidah13@gmail.com. Mobile: +6282234721294.

DOI: https://doi.org/10.26911/theicph.2018.01.65


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