Survival Analysis on The Effect of Nutritional Status among People Living with HIV/AIDS in Jayapura, Papua


 Dian Winiarti1), Ambar Mudigdo2), Bhisma Murti1)

 

1)Masters Program in Public Health, Universitas Sebelas Maret

2)Faculty of Medicine, Universitas Sebelas Maret

 

ABSTRACT

Background: Malnutrition is a common occurrence in HIV/AIDS cases and is a major cause of morbidity and mortality. Well-nourished patients are best able to withstand me­dical treatment, which is particularly important in HIV/AIDS. It has been suggested that weight loss reduces the ability of patients to be treated effectively with anti­re­tro­viral therapy. The purpose of this study was to examine the effect of nutritional status on survival among people living with HIV/AIDS in Jayapura, Papua.

Subjects and Method: A cohort retrospective study was carried out at VCT room Dok II Ge­ne­ral Hospital, Jayapura, Papua, from May to June 2018. A sample of 97 people living with HIV/AIDS (PLWH) with malaria co-infection recurrence and 86 PLWH was selected by fixed di­sease sampling. The dependent variable was time to death. The independent variable was nutri­ti­onal status. Confounding factors included drug taking adherence, economics status, clean and healthy behaviour, use of bed nest, and residual spray. The data were obtained from medical re­cord and questionnaire. The data were analyzed by Cox regression model.

Results: Risk of death in PLWH with malaria co-infection decreased with good nutritional status (HR= 0.25; 95% CI= 0.54 to 0.12; p<0.001) after adjusting for the effect of adherence to ARV (HR= 0.63; 95% CI= 0.93 to 0.43; p= 0.018).

Conclusion: Risk of death in PLWH with malaria co-infection decreases with good nutritional status after adjusting for the effect of adherence to ARV.

Keywords: survival, co-infection, nutritional status, HIV/AIDS, people living with HIV/AIDS

Correspondence: Dian Winiarti. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36 A, Surakarta 57126, Central Java, Indonesia. Email: Dianwiniarti@gmail.com.

Mobile: +6281344266960

DOi: https://doi.org/10.26911/theicph.2019.01.11

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