Effect of Aloe Vera Drink on Short Term Memory among Patients with Metabolic Syndrome

Faridah Hanum Nasution


Department of Nutrition, Masters in Nutrition Science, Faculty of Medicine, Universitas Diponegoro



Background: Various risk factors of metabolic syndrome (MS) increase oxidative stress, causing damage to tissue and neuron cells, which results in decreased cognitive func­tion (memory). Flavonoids, anthraquinone, and polysaccharides are useful in pre­ven­t­ing in­sulin resistance, chronic inflammation, and oxidative stress. Flavonoids have the potential to enhance memory and learning by activating kinases. Aloe vera were shown in previous stu­dies to contain various biologically active substances like e.g. phe­nol­­carboxylic acids and flavonoids. This study aimed to determine the effect of Aloe vera drink on short term memory among patients with metabolic syndrome.

Subjects and Method:This was a quasi experiment. A total of 38 patientswith MS aged 35-38 years was selected for this study, consisting 19 patients in the intervention group and 19 patients in the control group. Aloe vera drink was given to patients in the in­ter­­vention group 165 g/day for 30 days. The dependent variables were triglyceride, HDL-C, MDA, and memory. The independent variable was Aloe vera. Difference in means were tested by t test. Pearson correlation was used as a measure of association.

Results:After administration of Aloe vera,triglyceride and MDA levels decreased sig­ni­­ficantly, and HDL-C level increased significantly, in the intervention group. Memory was inversely correlated with triglyceride (r= -0.31; p= 0.041) and MDA (r= -0.27; p= 0.009). Memory was positively correlated with HDL-C (r= 0.47; p= 0.003).

Conclusion:Aloe vera drink is effective to decrease triglyceride and MDA and to in­crease HDL-C, and subsequently to increase memory.

Keywords: short-term memory, metabolic syndrome, Aloe vera drink.

Correspondence: Faridah Hanum Nasution. Department of Nutrition, Master of Nutrition Science Program, Faculty of Medicine, Diponegoro University. Jl. Tirta sari No. I C. Tembalang, Semarang50275, Central Java. Email:faridahhanum395@gmail.com. Mobile: 08529­67­08301.

DOI: https://doi.org/10.26911/theicph.2019.05.13

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