Effect of Celery (Apium Graveolens) on The Reduction of Blood Pressure: A Systematic Review


Elma Marsita

 

Masters Program in Midwifery, School of Health Polytechnics, Ministry of Health, Semarang

 

ABSTRACT

Background: High blood pressure, also called hypertension, is one of the most com­mon causes of early death in symptom-free adults. About 75 to 80% of the world popu­lation use herbal medicines for primary health care because of their better acceptability with human body and lesser side effects. Celery or Apiumgraveolens is a plant from the family of Apiaceae that has been used to lower blood preasure. This study aimed to review systematically the effect of Apiumgraveolens on the reduction of blood pres­sure.

Subjects and Method: This was a systematic review. The theme of this study was the be­ne­fits of non-pharmacological treatment of celery extract in hypertensive expe­ri­men­tal animal. A total of 6 articles were obtained from Science Direct, CINAHL, Pub Med, Elsevier (SCOPUS), and Pro Quest databases. Articles were specified based on inclusion and exclusion criteria. The inclusion criteria were articles published in English, time period around 2008 to 2018, quantitative study, non-duplicate articles published by Science direct, CINAHL, Pub Med, Elsevier (SCOPUS), and Pro Quest, and obligated to the objective of this study.

Results: Celery extract had a significant effect to help lower the blood pressure in hy­per­­tension. The celery was extracted with ethanol, hexane, ethyl acetate, methanol, and pure water. All study were used laboratory experiments method with experimental ani­mal. Most of them showed hypotensive effects through bradycardia and vasodilation from the administration of celery extract.

Conclusion: Celery extract has a significant effect to help lower the blood pressure in ex­perimental animal with hypertension.

Keywords: celery, Apiumgraveolens, blood pressure, hypertension, hypotensive effect

Correspondence: Elma Marsita. Masters Program in Midwifery, School of Health Polytechnics, Ministry of Health, Semarang, Central Java. Email: elmamarsita93@gmail.com. Mobile: 089693­47­9630.

DOI: https://doi.org/10.26911/theicph.2019.05.17 

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