Biopsychosocial Factors Associated with the Occurrence of Female Infertility

Suci Arsita Sari1), Uki Retno Budihastuti2), Eti Poncorini Pamungkasari3) 


1)Masters Program in Public Health, Universitas Sebelas Maret

2)Department of Obstetrics and Gynecology, Dr. Moewardi Hospital, Surakarta

3)Faculty of Medicine, Universitas Sebelas Maret, Surakarta



Background: Infertility is a complex and situational crisis that is generically psychologically threatening, emotionally stressful, financially challenging, and physically painful most of the times due to diagnostic-curative operations undergone. The relationship between lifestyle factors and fertility has been studied from differing methodological approaches. However, studies about biopsychology factors on infertility are still scarce. This study aimed to examine biopsychosocial factors associated with the occurrence of female infertility.

Subjects and Method: A case control study was carried out at Dr. Moewardi hospital, Surakarta, Central Java, from May to June 2019. A sample of 200 women was selected by fixed disease sampling, consisting of infertile and fertile women. The dependent variable was female infertility. The independent variables were age, body mass index (BMI), polycystic ovary syndrome (PCOS), metabolic disease, uterine myoma, and employment status. The data were collected from the medical record and questionnaire. The data were analyzed by a multiple logistic regression.

Results: The likelihood of female infertility increased with age ≥35 years old (OR=9.05; 95% CI= 2.61 to 31.39; p= 0.001), being employed (OR= 8.29; 95% CI= 2.25 to 30.48; p= 0.001), BMI ≥25 (OR= 8.16; 95% CI= 2.44 to 27.29; p= 0.001), PCOS (OR= 117.34; 95% CI= 10.31 to 1334.83; p<0.001), endometriosis (OR= 5.01; 95% CI= 1.17 to 21.38; p= 0.029), uterine myoma (OR= 6.59; 95% CI= 1.76 to 24.67; p= 0.005), and metabolic disease (OR= 15.39; 95% CI= 4.02 to 58.84; p<0.001).

Conclusion: The likelihood of female infertility increases with age ≥35 years old, employment, BMI ≥25, PCOS, endometriosis, uterine myoma, and metabolic disease.

Keywords: female infertility, polycystic ovary syndrome, endometriosis

Correspondence: Suci Arsita Sari. Masters Program in Public Health. Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: Mobile: 085786179994.


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