Family History with Diabetes Mellitus and the Gestational Diabetes Mellitus: Meta-Analysis

Ummu Fatihah Ammutammima1), Didik Gunawan Tamtomo2), Bhisma Murti1)


1)Masters Program in Public Health, Universitas Sebelas Maret
2)Faculty of Medicine, Universitas Sebelas Maret



Background: Gestational diabetes mellitus (GDM) is a major public health problem because of its associated complications during pregnancy. Studies have suggested that women with positive parental history of diabetes may be predisposed to an increased GDM risk. This study aimed to examine the correlation between family history with diabetes mellitus and the gestational diabetes mellitus.

Subjects and Method: This was a meta-analysis and systematic review. The study was collected articles from PubMed, Science Direct, and Google Scholar databases, from year 2017 to 2020. Keywords used “gestational diabetes mellitus” OR “GDM” AND “pregnancy induced diabetes” AND “family history of diabetes” AND “crosssectional”. The study subject was pregnant women. Intervention was family history with diabetes mellitus with comparison no family history of diabetes mellitus. The study outcome was gestational diabetes mellitus. The articles were selected by PRISMA flow chart. The quantitative data were analyzed by ReVman 5.3.

Results: 7 studies from Kuwait, Ethiopia, Fiji, Malaysia, and China, reported that family history with diabetes mellitus increased the risk of gestational diabetes mellitus (aOR= 1.68; 95% CI= 0.87 to 3.26; p= 0.120).

Conclusion: Family history with diabetes mellitus increases the risk of gestational diabetes mellitus.

Keywords: gestational diabetes mellitus, pregnancy induced diabetes, family history of diabetes

Correspondence: Ummu Fsatihah Ammutammima. Masters Program Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: Mobile: 081717252573.


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