Meta Analysis the Effect of Type 2 Diabetes Mellitus on Covid-19 Mortality

Oktaviana Kurniawati1), Hanung Prasetya2), Bhisma Murti1)


1)Masters Program in Public Health, Universitas Sebelas Maret

2)Health Polytechnics, Ministry of Health Surakarta



Background: People with type 2 diabetes are known more susceptible to infections and require longer hospitalization. It resulted in an overall worse prognosis. As the COVID-19 pandemic has progressed, a similar pattern of a worse prognosis for people with diabetes who contract COVID-19 has been reported in population-based studies, with an increased risk of intensive care admission and worse mortality outcome. This study aimed to describe the relationship between type 2 diabetes mellitus on COVID-19 mortality.

Subjects and Method: This was a systematic review and meta analysis. Articles published from 2020 to 2021 in PubMed, Google Scholar, JAMA, Willey, and Science Direct databases were collected by PRISMA guideline. Keywords used (Type 2 diabetes mellitus OR diabetic) AND (mortality OR death) AND (COVID-19 /OR Coronavirus OR SARS-CoV-2) AND (“adjusted odds ratio” OR “aOR”. The inclusion criteria were full text in English language and observational studies. Selected articles were assessed using Review Manager (RevMan 5.3).

Results: 6 cohort studies were included for meta-analysis. This study showed that people with type 2 DM comorbidity had possibility 1.93 times to death caused by COVID-19 than those without type 2 DM (aOR= 1.93; 95% CI= 1.28 to 2.90; p = 0.002).

Conclusion: Type 2 DM comorbidity increases the risk of COVID-19 mortality.

Keywords: type 2 diabetes mellitus, COVID-19, mortality

Correspondence: Oktaviana Kurniawati. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: Mobile: 085865463742.


Share this :

View PDF