Abstract
Background: Dengue Hemorrhagic Fever (DHF) is one of the endemic diseases with the highest cases in Indonesia. The incidence of DHF has increased more than 8-fold over the past two decades by 2020, from 505,430 cases in 2000, to more than 2.4 million in 2010, and 5.2 million in 2019. This study aimed to analyze recovery rate of patients with DHF during the COVID-19 period and the associated factors.
Subjects and Method: This study was a retrospective cohort study conducted at Dr. M. Djamil, Padang, West Sumatera. A sample of 52 patients with DHF during the COVID-19 period (March 2020-February 2022) were selected for this study. The dependent variable was recovery. The independent variables were age, sex, duration of fever, thrombocyte level, hematocrit level, and insurance status. The data were collected from the medical record. The data were analyzed by Kaplan-Meier and Cox proportional hazard model.
Results: The average recovery was 10 days. The recovery rate improved with age >14 years (HR= 2.73; CI 95%= 1.05 to 7.10; p= 0.039). The recovery rate worsened with longer duration of fever (HR= 0.12; 95% CI= 0.03 to 0.54; p= 0.006), thrombocyte level <100,000 (HR= 0.88; 95% CI= 0.26 to 3.29; p= 0.006), and hematocrit level >20% (HR= 0.21; 95% CI= 0.05 to 0.93; p= 0.040). The associations between DHF and sex (HR= 1.69; CI 95%= 0.63 to 4.59; p= 0.299) and insurance status (HR= 1.29; CI 95%= 0.29 to 5.65; p= 0.739) were statistically non-significant.
Conclusion: The average recovery for DHF is 10 days. The recovery rate improves with age >14 years. The recovery rate worsens with longer duration of fever, thrombocyte level <100,000, and hematocrit level >20%. The associations between DHF and sex and insurance status are statistically non-significant.