Background: The severity of COVID-19 is highly variable, ranging from asymptomatic in��fec�tion to a complicated and sometimes lethal course. Case series (hospital based stu�dies) have identified risk factors associated with poor outcomes, including older age, male sex and certain underlying diseases. The aimed of this study was to determine fac�to�rs associated with severity of covid-19 infection.
Subjects and Method: This was a cross-sectional study conducted at Dr. M. Djamil Hospital Padang, West Sumatra, from March 2020 to February 2021. A random sample of 95 patients were selected for this study. The dependent variable was severity of CO�VID-19. The independent variables were age, sex, hypertension status, diabetes mellitus sta�tus, cardiovascular disease status, respiratory disease status, and smoking history. The data were obtained from medical record and analyzed reporting by chi-square and des�cribed by the Prevalence Odds Ratio (POR).
Result: The severity of COVID-19 infection increased with older age (POR= 4.52; 95% CI= 1.48 to 12.1), cardiovascular disease (POR= 5.99; 95% CI= 1.67 to 21.4), and respire�to�ry disease (POR= 6.61; 95% CI= 2.09 to 20.8).
Conclusion: The severity of COVID-19 infection increased with older age, cardio�vascu�lar disease, respiratory disease.