Abstract
Background: Excessive consumption of alcoholic drinks has long-term health impacts, one of which is increasing blood cortisol levels, thereby increasing the activity of the Renin-Angiotensin Aldosterol System (RAAS) and causing an increase in blood pressure. This study aimed to estimate the relationship between excessive alcohol consumption and hypertension.
Subjects and Method: This meta-analysis was conducted using a PICO research question. Population: Adults. Intervention: Excessive alcohol consumption. Comparison: No excessive alcohol consumption. Outcome: Hypertension. The articles were searched from 3 databases PubMed, Google Scholar, and Science Direct. Keywords used "Alcohol Consumption" AND "Hypertension" AND "Adults". The inclusion criteria included full-text papers, cross-sectional studies, multivariate analysis with adjusted Odds Ratio (aOR), and published from 2013 to 2022. The articles were analyzed using Review Manager 5.3.
Results: Eleven primary studies were included in this meta-analysis from Thailand, Japan, China, Korea, Nepal, Mongolia, Greece, Finland, the United States, and Brazil. Consumption of excessive alcohol increased the risk of developing hypertension among adults 1.23 times compared to those who did not consume alcohol, and it was statistically significant (aOR= 1.23; 95% CI= 1.05 to 1.44; p=0.001).
Conclusion: Consuming excessive alcohol increases the risk of developing hypertension among adults.
Keywords: alcohol consumption, hypertension, adult.
Correspondence:
Ayun Widya Rizki. Master’s Program in Public Health, Universitas Sebelas Maret. Jl. Ir sutami 36A, Surakarta 57126, Indonesia. Email: ayun.widya.rizki@gmail.com. Mobile: +628114331710.
Article Data
