Abstract
Background: Tuberculosis (TB) is an infectious disease that most often affects the lungs and is caused by a type of bacteria. It spreads through the air when infected people cough, sneeze, or spit. The quality of life of tuberculosis patients is influenced by various things, including human immunodeficiency virus (HIV) comorbidity. This study aimed to estimate the effect of HIV comorbidity on the quality of life in patients with tuberculosis.
Subjects and Method: This meta-analysis was conducted using a PICO research question. Population: TB patients. Intervention: HIV. Comparison: Non-HIV. Outcome: Quality of life. The articles were searched from databases PubMed, Science Direct, and Google Scholar published from 2012 to 2023. Keywords used "Quality of life" AND "Tuberculosis patients" AND "HIV-TB" AND "Cross-sectional”. The inclusion criteria included were full-text paper, English and Indonesian, multivariate analysis with adjusted Odds Ratio (aOR), and QOL from various brief questionnaires. The articles were analyzed using Review Manager 5.3.
Results: The meta-analysis included 9 primary studies from Ethiopia, Uganda, and South Africa. The total sample size was 10,714 tuberculosis patients. TB patients with HIV comorbid had 1.77 times as much risk for poor quality of life compared to those without HIV comorbidity (aOR=1.77; 95% CI= 0.98 to 3.17; p=0.060).
Conclusion: HIV comorbidity increases the risk of poor quality of life in tuberculosis patients.
Keywords: HIV comorbid, quality of life, tuberculosis patients.
Correspondence:
Wardhatul Livia. Master’s Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 51726, Central Java. Email: wardhatullivia98@gmail.com. Mobile: +6285803308509.
Article Data
