Background: According to the World Health Organization, alcohol is consumed by more than 55% of adults, and alcoholism affects 140 million people globally. Many experimental studies confirmed that ethyl alcohol causes glomeruli and renal tubule damage. However, in epidemiological research, there are many inconsistent findings on alcohol consumption and chronic kidney disease (CKD). The purpose of this study was to estimate the impact of excessive alcohol consumption on chronic kidney disease.
Subjects and Method: A systematic review and meta-analysis performed iterative searches using the following repositories for published cross-sectional studies during 2017–2022: PubMed, Google Scholar, and Science Direct. The PICO model was formulated to determine the eligibility of literature searches. Population: Adults. Intervention: Excessive alcohol consumption. Comparison: Tolerable alcohol consumption. Outcome: Chronic kidney disease. Keywords used for the article search were "alcohol consumption" AND "chronic kidney disease" AND adult AND "cross sectional". The pooled adjusted odds ratio (aOR) was calculated using RevMan 5.3.
Results: A meta-analysis included 9 cross-sectional studies from Taiwan, Japan, and South Korea. Excessive alcohol consumption significantly increased the risk of chronic kidney disease in the adult population (aOR= 1.20; 95% CI= 0.97 to 1.50; p= 0.001).
Conclusion: Excessive alcohol consumption significantly increases the risk of chronic kidney disease in the adult population.
Keywords: excessive alcohol consumption, chronic kidney disease, adult population
Annisa Risnasari. Master’s Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: firstname.lastname@example.org. Mobile: +6281542942011.